NFL Slate Analysis — Monday, September 21, 2026
Monday, September 21, 2026 · NFL
These games have been played. Picks and prices, where shown, are AiQ's from before each game started. See how they finished in the NFL recaps.
The NFL slate for Monday, September 21, 2026 has 1 game, at 7:15 PM CT. AiQ has a moneyline pick on it. None of AiQ's picks on this slate has a price on record above fair value. Each price is the one AiQ valued the pick at when it last priced the game.
Every game
New York Giants at Los Angeles Rams
7:15 PM CT at SoFi Stadium.
- Moneyline: AiQ gives Los Angeles Rams a 63% confidence rating to beat New York Giants, its own model's number rather than a market price. Calibrated against the market and graded results, that is a 72.6% chance; the betting market, with the margin removed, has 73.2%. The best price, -285 at BetMGM, is priced below the fair price of -265 (−1.9% value).
- Total: AiQ gives the over 47.5 points a 57% confidence rating, its own model's number rather than a market price. Calibrated against the market and graded results, that is a 50.8% chance; the betting market, with the margin removed, has 48.8%. The price on record, -105, is priced below the fair price of -103 (−0.8% value).
- Spread: AiQ gives New York Giants +6.5 a 58% confidence rating to cover, its own model's number rather than a market price. Calibrated against the market and graded results, that is a 46.8% chance; the betting market, with the margin removed, has 48.8%. The best price, -102 at Caesars, is priced below the fair price of +114 (−7.3% value).