MLS Slate Analysis — Wednesday, October 21, 2026

Wednesday, October 21, 2026 · MLS

These matches have been played. Picks and prices, where shown, are AiQ's from before each match started. See how they finished in the MLS recaps.

The MLS slate for Wednesday, October 21, 2026 has 1 match, at 6:00 PM CT. AiQ has a moneyline pick on it. Of AiQ's picks on this slate, 2 have a price on record above fair value. Each price is the one AiQ valued the pick at when it last priced the game.

Best value

Every match

D.C. United vs FC Cincinnati

6:00 PM CT at TQL Stadium.

D.C. United have won 7, drawn 12 and lost 10 of their 29 matches this season, winning one of the last five. FC Cincinnati have won 9, drawn 9 and lost 11 of their 29 matches this season, winning one of the last five.

Match previews and recaps