MLB Slate Analysis — Wednesday, September 16, 2026

Wednesday, September 16, 2026 · MLB

These games have been played. Picks and prices, where shown, are AiQ's from before each game started. See how they finished in the MLB recaps.

The MLB slate for Wednesday, September 16, 2026 has 15 games, the first at 12:00 PM CT. No AiQ pick priced before the start is on record for any of them, so they are listed without picks.

Every game

• Chicago White Sox at Cleveland Guardians, 12:00 PM CT at Progressive Field.
• San Francisco Giants at St. Louis Cardinals, 12:15 PM CT at Busch Stadium.
• New York Yankees at Minnesota Twins, 12:40 PM CT at Target Field.
• Detroit Tigers at Toronto Blue Jays, 2:07 PM CT at Rogers Centre.
• Athletics at Tampa Bay Rays, 5:40 PM CT at Tropicana Field.
• Los Angeles Dodgers at Cincinnati Reds, 5:40 PM CT at Great American Ball Park.
• Milwaukee Brewers at Pittsburgh Pirates, 5:40 PM CT at PNC Park.
• Philadelphia Phillies at Washington Nationals, 5:45 PM CT at Nationals Park.
• Baltimore Orioles at New York Mets, 6:00 PM CT at Citi Field.
• Atlanta Braves at Chicago Cubs, 6:40 PM CT at Wrigley Field.
• Boston Red Sox at Texas Rangers, 7:05 PM CT at Globe Life Field.
• Kansas City Royals at Houston Astros, 7:10 PM CT at Daikin Park.
• San Diego Padres at Colorado Rockies, 7:40 PM CT at Coors Field.
• Seattle Mariners at Los Angeles Angels, 8:38 PM CT at Angel Stadium.
• Miami Marlins at Arizona Diamondbacks, 8:40 PM CT at Chase Field.

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