Dallas Cowboys vs Indianapolis Colts Prediction, Picks & Odds — Nov 8

Sun, Nov 8, 1:00 PM ET · Lucas Oil Stadium · NFL

Open the game card for live odds, every market and the full prediction.

Dallas Cowboys at Indianapolis Colts is on Sunday, November 8, 2026, at Lucas Oil Stadium. Averaged over the outcomes the betting lines imply, the projected score is Dallas Cowboys 29, Indianapolis Colts 23. That is an average, not a pick.

The story

The Indianapolis Colts have won 2 of their 8 games this season, losing the last four. The Dallas Cowboys have won 3 of their 8 games this season, winning two of the last five.

Matchups to watch

• Mismatch in scoring. The Dallas Cowboys averaged 27.4 points per game this season, the 7th most in the NFL, and the Indianapolis Colts allowed 27.8 points per game, the 3rd most.
• Weakness against weakness in total yards. The Indianapolis Colts averaged 291.1 yards per game this season, the 7th fewest in the NFL, and the Dallas Cowboys allowed 385.4 yards per game, the most.

Moneyline

The betting market, with the margin removed, gives Dallas Cowboys a 69.3% chance to beat Indianapolis Colts. AiQ's moneyline pick is the side the consensus favors. The price on record is -225.

Total

The betting market, with the margin removed, puts the over 51.5 points at 49.7% and the under at 50.3%. That is near a coin flip, and AiQ's read is the market's own, so AiQ has no edge on the total. AiQ's projected total, 52.2 points, sits on the 51.5 line.

Spread

The betting market, with the margin removed, gives Dallas Cowboys -5.5 a 50.1% chance to cover and Indianapolis Colts +5.5 49.9%. That is near a coin flip, and AiQ's read is the market's own, so AiQ has no edge on the spread.

Trends in play

Recent totals lean over. The Dallas Cowboys went over the total in 8 of their last 10 games.

These come from the closing lines of this season and last. They are context, not the reason for AiQ's picks, and the books price them in.