Louisville Cardinals defeat Villanova Wildcats 59-13: Recap, Betting Results & AiQ Picks

Fri, Sep 11, 2026 · NCAAF · Villanova Wildcats 13, Louisville Cardinals 59

Louisville Cardinals beat Villanova Wildcats 59–13. No spread was published for this contest and the game's total line was not provided, so coverage and over/under outcomes are not applicable.

Villanova Wildcats vs. Louisville Cardinals final score and game recap

Louisville dominated from the opening quarter, building a 17–3 lead and never relinquishing control. The Cardinals extended their advantage to 31–10 by halftime, then outscored Villanova 28–3 over the final two quarters to seal a 59–13 rout at L&N Federal Credit Union Stadium.

The scoring progression told the story: Louisville posted 17, 14, 14, and 14 points in successive quarters, while Villanova managed only 3, 7, 3, and 0. The Wildcats' early deficit proved insurmountable.

How did AiQ's Villanova Wildcats vs. Louisville Cardinals predictions do?

AiQ finished 2–3 on this game.

The model correctly identified Louisville as the winner but went 1–3 on individual touchdown props.

Villanova Wildcats vs. Louisville Cardinals player prop results

AiQ went 1–3 on player props, netting a loss of $247.37 on $100 per pick.

Villanova Wildcats sit 0–1 overall and 0–1 on the road. With only one game played, ATS and over/under records cannot be evaluated.

Louisville Cardinals are 1–1 overall, 1–0 at home and 0–1 away/neutral. The Cardinals are 1–0 against the spread and 1–0 on the over/under, each based on a single game with a recorded closing line.

What's next for Villanova Wildcats and Louisville Cardinals?

Louisville will host the SMU Mustangs on Saturday, September 19. Villanova's next opponent has not been disclosed.