Miami Marlins defeat St. Louis Cardinals 4-1: Recap & Betting Results

Wed, Apr 22, 2026 · MLB · St. Louis Cardinals 1, Miami Marlins 4

The Miami Marlins beat the St. Louis Cardinals 4-1 on Wednesday, April 22, 2026, at loanDepot park. The Miami Marlins covered the run line as 1.5-run favorites. The game went under the closing total of 8, with 5 runs combined.

St. Louis Cardinals vs. Miami Marlins final score and game recap

The Miami Marlins won by 3 runs.

The leading performers, from the box score:

Who covered the spread in St. Louis Cardinals vs. Miami Marlins?

The Miami Marlins covered the run line as 1.5-run favorites, winning by 3 runs.

The run line opened and closed at Miami Marlins -1.5.

Did St. Louis Cardinals vs. Miami Marlins go over or under the total?

The game went under: 5 runs combined against a closing total of 8, under by 3.

The total opened at 8.5 and closed at 8.

This result left the St. Louis Cardinals 14-10 in the 2026 regular season (7-5 at home, 7-5 away or at neutral sites). Against the run line, they covered in 13 of 23 games with a closing line on file. Their games went over the closing total 12 times and under 9 times, with 2 pushes.

This result left the Miami Marlins 12-13 in the 2026 regular season (10-6 at home, 2-7 away or at neutral sites). Against the run line, they covered in 10 of 24 games with a closing line on file. Their games went over the closing total 13 times and under 9 times, with 2 pushes.

What's next for St. Louis Cardinals and Miami Marlins?

Next for the St. Louis Cardinals: the Seattle Mariners at home on Friday, April 24, 2026. Next for the Miami Marlins: at the San Francisco Giants on Friday, April 24, 2026.