Patriots vs Bears, Duke vs Virginia and 3 more: AiQ Picks and Predictions (Week of October 22)
ProphetAiQ Team · 2026-10-22
AiQ's picks for Patriots vs Bears, Duke vs Virginia, UTSA vs Tulane, Chiefs vs Seahawks, Cowboys vs Eagles, with the price and the facts behind each. Video…
ProphetAiQ's preview video from October 22, 2026 goes through AiQ's picks for 5 games. Below is each game with the picks as they stood when the video was made, and how they graded once the game was played.
New England Patriots at Chicago Bears
The Chicago Bears beat the New England Patriots 30-24 on Thursday, October 22, 2026, at Soldier Field. The Chicago Bears covered the spread as 3-point favorites. The game went over the closing total of 50.5, with 54 points combined.
AiQ's picks when the video was made, and how they graded:
- Moneyline: Chicago Bears, priced below fair: a win.
Duke Blue Devils at Virginia Cavaliers
Friday, October 23, 2026, at Scott Stadium.
AiQ's picks when the video was made:
- Moneyline: Virginia Cavaliers, priced below fair.
- Total: Over 47.5 points.
- Spread: Virginia Cavaliers -1.5.
The story
The Duke Blue Devils have won 4 of their 6 games this season. The Virginia Cavaliers have won 4 of their 7 games this season.
Every market and price for this game
UTSA Roadrunners at Tulane Green Wave
Saturday, October 24, 2026, at Yulman Stadium.
AiQ's picks when the video was made:
- Moneyline: UTSA Roadrunners, priced below fair.
- Total: Over 51.5 points.
- Spread: UTSA Roadrunners -2.5.
The story
The UTSA Roadrunners have won 6 of their 7 games this season, winning the last four. The Tulane Green Wave have won 3 of their 6 games this season. When these teams last met, on October 30, 2025, the UTSA Roadrunners won 48-26 at home.
Matchups to watch
- Weakness against weakness in total yards. The Tulane Green Wave averaged 332.0 yards per game this season, the 24th fewest of 138 FBS teams, and the UTSA Roadrunners allowed 400.0 yards per game, the 27th most.
Trends in play
Recent totals lean over. The UTSA Roadrunners went over the total in 7 of their last 10 games.
These come from the closing lines of this season and last. They are context, not the reason for AiQ's picks, and the books price them in.
Every market and price for this game
Kansas City Chiefs at Seattle Seahawks
Sunday, October 25, 2026, at Lumen Field.
AiQ's picks when the video was made:
- Moneyline: Kansas City Chiefs, priced below fair.
- Total: Under 42.5 points.
- Spread: Seattle Seahawks -2.5.
The story
The Kansas City Chiefs have won all five of their games this season. The Seattle Seahawks have won 3 of their 6 games this season. The Seattle Seahawks come in with more rest: their last game was on October 15, ten days before this one, while the Kansas City Chiefs played seven days before.
Matchups to watch
- Strength against strength in total yards. The Kansas City Chiefs averaged 414.0 yards per game this season, the most in the NFL, and the Seattle Seahawks allowed 237.3 yards per game, the fewest.
Trends in play
Recent totals lean under. The Kansas City Chiefs went under the total in 8 of their last 10 games.
These come from the closing lines of this season and last. They are context, not the reason for AiQ's picks, and the books price them in.
Every market and price for this game
Dallas Cowboys at Philadelphia Eagles
Monday, October 26, 2026, at Lincoln Financial Field.
AiQ's picks when the video was made:
- Moneyline: Dallas Cowboys, priced below fair.
- Total: Over 44.5 points.
- Spread: Dallas Cowboys -4.5.
The story
The Philadelphia Eagles have won 2 of their 6 games this season, losing the last four. The Dallas Cowboys have won 2 of their 6 games this season. When these teams last met, on November 23, 2025, the Dallas Cowboys won 24-21 at home.
Matchups to watch
- Mismatch through the air. The Dallas Cowboys averaged 267.2 passing yards per game this season, the 6th most in the NFL, and the Philadelphia Eagles allowed 244.5 passing yards per game, the 7th most.
- Weakness against weakness on the ground. The Philadelphia Eagles averaged 82.2 rushing yards per game this season, the 4th fewest in the NFL, and the Dallas Cowboys allowed 149.8 rushing yards per game, the most.
Trends in play
Recent totals lean over. The Dallas Cowboys went over the total in 8 of their last 10 games.
Against the spread, the records pull in opposite directions. The Philadelphia Eagles failed to cover the spread in 7 of their last 10 games. Meanwhile, the Dallas Cowboys failed to cover the spread in 7 of their last 10 games.
These come from the closing lines of this season and last. They are context, not the reason for AiQ's picks, and the books price them in.